Equelle Review 2025: Can This Plant-Based Supplement Help Relieve Menopausal Symptoms and Improve Quality of Life?

Equelle Ingredient Analysis

Supplement Facts

Equelle claims to be a natural supplement that provides hormone-free relief from menopause symptoms. But does it actually work? To find out, we examined its key ingredient categories based on their intended benefits:

• Hormone & Mood Support – Targets hormone balance, energy, and emotional stability.
• Bone & Muscle Support – Helps reduce muscle aches and support bone health.
• General Wellness Support – Provides essential nutrients for overall health.

Ingredient Analysis—Hormone & Mood Support

S-equol is the key ingredient in Equelle. It is made from fermented soy and mimics the effects of estrogen in the body. Theoretically, this may help alleviate some menopause symptoms like hot flashes and night sweats.

Studies show that S-equol may help ease menopause symptoms like hot flashes, especially when taken at 10 mg twice a day. While early research is promising, the studies have been small, and more research is needed to confirm its effectiveness. Plus, it is not effective for everyone.

While it may temporarily help some people, its long-term effectiveness is still debated. Because S-equol is this supplement's major selling point, we’re already skeptical about its true effectiveness.

We do not approve of this ingredient.

Ingredient Analysis—Bone & Muscle Support

Equelle adds 240 mg of Calcium to its formula. Calcium is essential in supporting bone health, and studies have shown it helps maintain bone density, especially during menopause when the risk of bone loss increases. However, most experts recommend 1,200 mg of Calcium daily for menopausal women, so the 240 mg in Equelle is significantly lower than what is needed for optimal bone support.

According to Sarah Shealy, MSN, CNM, MSCP, Menopause Specialist

Calcium is crucial for maintaining bone health, especially during menopause when women are at higher risk for bone loss. While the 240 mg of calcium in Equelle may offer some benefit, it's far below the recommended daily intake of 1,200 mg for menopausal women. To support optimal bone density, a higher dose of calcium, ideally paired with Vitamin D for better absorption, is generally advised.

Advertisement

There’s another downside. While Calcium is essential for bone health, it works best when paired with Vitamin D. Vitamin D is important because it helps the body absorb Calcium properly. Without Vitamin D, the effectiveness of Calcium is significantly reduced.

Unfortunately, Equelle doesn’t include Vitamin D, making this blend less effective than it could be.

This formula also contains Fermented Soy Germ. We did some research to see how Soy could be used as a menopause supplement. What we found was subpar at best.

Soy is known for its phytoestrogen content and may mildly regulate hormones and bone by increasing bone density. However, research showing its effectiveness is weak.

On this note, we do not approve this blend.

We Tried Equelle

Equelle

To get a better sense of how Equelle performs in real life, I asked one of my coworkers to try it for herself. She’s in her early 50s and has been dealing with menopause symptoms like hot flashes, poor sleep, and mood swings.

She started taking Equelle as directed (two tablets daily with water). During the first two weeks, she noticed some improvement in her mood and said she felt “a little less irritable.” However, there was no significant change in her energy levels or sleep quality during that time.

By the end of the first month, she felt that her mood was more stable, and her hot flashes had decreased in intensity. While she still had hot flashes, they were less frequent and not as strong. That said, she still didn’t see any noticeable changes in her energy or sleep.

In the second month, the benefits seemed to have reduced. While Equelle helped maintain her mood stability and seemed to lessen her hot flashes slightly, it didn’t fully relieve her symptoms. She still had days where she felt tired, had trouble sleeping, or experienced mild night sweats.

Overall, she rated her experience a 5 out of 10. Equelle provided mild relief but didn’t make a big enough difference for her. She felt it might work better for women with milder menopause symptoms, but for more severe symptoms, it didn’t seem to offer enough help.

Side Effects & Safety of Equelle

Equelle is made with plant-based ingredients and does not contain caffeine, synthetic hormones, or artificial additives. This makes it a good option for women who are sensitive to stimulants or prefer a natural alternative to traditional hormone therapies.

That said, some users have reported mild side effects when they first started taking Equelle. These include digestive discomfort, bloating, or light headaches. These effects typically go away as the body adjusts to the supplement.

While the formula is generally safe for most people, Equelle may not be suitable for everyone. Women with hormone-sensitive conditions, those on prescription medications, or individuals with soy allergies should consult with a healthcare provider before using the product.

Equelle appears to be safe for most adults, but as with any supplement, individual experiences may vary.

Real Customer Reviews

Amazon tends to offer more reliable customer feedback than a brand’s official website, mainly because it includes verified purchases and unfiltered experiences.

At the time of this review, Equelle is rated 3.9 out of 5 stars on Amazon, based on 412 global reviews. Many users report mild improvements in hot flashes and mood, but some have experienced minimal changes or mild side effects.

A top positive review from a verified purchaser, So252, who gave the product a 5/5 rating, states:

I started taking this supplement the same day I received them and began with 2 per day. Once my flashes subsided, I reduced to 1 per day. These are amazing. You will notice the reduction in hot flashes and night sweat within a week! I highly recommend, they are worth every cent.

A top negative review from another verified purchaser, London, who gave the product a 2/5 rating, states:

So unfortunately these made me so sick to my stomach and gave me the runs pretty badly so I was not able to tell if they would have helped hot flashes. It could have been just an individual reaction but there's no way I could continue to take these.

At the time of this writing, the company behind Equelle has a Trustpilot rating of No star, 0 reviews, and a BBB rating of A+, 0 reviews.

Given these mixed responses, Equelle may be helpful for some individuals looking for menopause symptom relief, but its results are not guaranteed. As always, it’s best to consult a healthcare provider before starting any new supplement.

Where to Find the Best Value

Equelle is available for purchase on the official website and on Amazon. Here are the pricing details:

From the official website:

• One bottle (30-day supply) costs $50
• A 30-day subscription (save 20%) costs $40 per month
• A 90-day subscription (save 26%) costs $37 per month and includes free shipping.

Amazon offers slightly better pricing upfront. However, purchases made there may not qualify for the full 1-year return policy that the official website offers. That’s because Amazon doesn’t always accept returns.

Compared to other menopause symptom relief supplements, Equelle’s pricing is reasonable, though it may not be the most cost-effective option for long-term use.

Pros & Cons of Equelle

Should You Buy Equelle?

Equelle has received mixed reviews. While some users report a reduction in hot flashes and improved sleep quality, others notice little to no change after consistent use. A few have also mentioned mild side effects like digestive discomfort or headaches. The supplement currently holds a 3.9 out of 5 rating on Amazon.

From an ingredient perspective, Equelle contains S-equol, a plant-based compound derived from soy, which shows some promise in relieving some menopause symptoms. However, research is limited, and more studies need to be done to determine its true effectiveness.

The formula also includes calcium, which is good for bone density. However, it doesn’t add any Vitamin D which makes the absorption of calcium possible. Other ingredients like Fermented Soy Germ also have less proven effectiveness when it comes to improving bone health.

Advertisement

The ingredients in Equelle are weak compared to those in Menocil. Menocil uses more well-established ingredients like Black Cohosh, Red Clover, Dong Quai, and Valerian Root. These ingredients are known to provide the best menopause hot flash relief while also effectively targeting other common symptoms like mood swings and sleep disturbances.

So, if you're looking for a menopause supplement that makes menopause easier to manage, you can’t go wrong with Menocil.