Bonafide Serenol Review: A Closer Look at Its Effectiveness for PMS and Menopause Relief

Introduction

The demand for natural, hormone-free solutions to support women through hormonal fluctuations has increased significantly in recent years. This is because many women are now seeking options that can help reduce mood swings, irritability, and uneasiness tied to PMS or perimenopause, without resorting to prescription medications.

This is why supplements like Bonafide Serenol have gained attention for their promise of menopause relief through plant-based ingredients.

Bonafide Serenol is advertised as a daily capsule that provides non‑hormonal support for women experiencing PMS and menopause symptoms. It claims to help reduce irritability and uneasiness while also addressing bloating and food cravings. The product also claims to improve sleep quality.

But does Bonafide Serenol actually deliver what it promises? Are its ingredients strong enough to justify the cost? And what do women who have used it have to say about it?

In this review, we’ll break down the formula, analyze its effectiveness, review real customer feedback, and evaluate its value. We’ll also compare it with other hormone‑free supplements on the market to help you decide whether it deserves a place in your health routine.

Let’s dive in!

Ingredient Analysis – Bonafide Serenol™

Bonafide Serenol™ Supplement Fact

We examined Serenol’s formula closely to assess how well each ingredient may support hormone-free relief from PMS-associated emotional symptoms. Below is our evidence-based evaluation of each ingredient:

Royal Jelly (24 mg, standardized to 5.8% 10‑HDA)

Royal Jelly is commonly promoted for general vitality and hormonal support, often at high therapeutic doses. In a trial involving 110 women, taking 1000 mg of Royal Jelly daily resulted in a decrease in PMS scores from 23.17 to 11.42 after two cycles, a drop of approximately 11.75 points. However, Serenol only provides 24 mg, far less than the tested amount.

Evidence for Royal Jelly’s mood impact remains inconsistent, and high doses (1000 mg+) appear necessary according to clinical trials.

We disapprove of this ingredient.

Purified Cytoplasmic Blend (contains PI‑82 & GC‑FEM pollen extracts)

Pollen extracts are valued in women’s health for their non‑hormonal support of PMS emotional symptoms. We observe clinically robust mood support from Sérélys®, a combined PI-82/GC-FEM pollen extract. In a randomized PMS trial, 101 women used Sérélys® for 4 months. Among 50 women who said irritability was their main PMS symptom, symptoms dropped by 47% based on doctor evaluations and 50% based on the women’s own reports, compared to placebo. This clearly indicates strong symptom relief of emotional distress.

Pollen extracts and chromium picolinate have shown promising results in supporting mood balance and reducing cravings. When used in the right doses, these ingredients can effectively address some of the emotional symptoms associated with PMS and menopause. — Dr. Lauren Streicher, OB/GYN, Clinical Professor of Obstetrics and Gynecology

Another study found a 48% improvement in irritability and low mood after 3 months of taking PI-82/GC-FEM. The extracts were well-tolerated and did not act like hormones.

We approve of this ingredient.

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Chromium (as Chromium Picolinate, 1000 µg)

Chromium picolinate is sometimes included in mood supplement protocols targeting menstrual-related mood fluctuations. In a randomized trial, 11 women received chromium from the mid-cycle to the onset of menses. On the HAM‑D scale, mood scores improved by about 30%, and several participants reported marked symptom relief. However, the study lasted only 1 month and had a tiny sample.

Serenol contains 1000 µg of chromium in a daily serving. However, findings detailing the importance of chromium for mood support remain unverified. With just 11 participants, the results cannot be generalized. No large-scale PMS trials confirm chromium’s effectiveness for mood swings or irritability. This means that chromium’s main benefit remains metabolic support rather than emotional symptom relief in PMS.

We disapprove of this ingredient.

We Tried Bonafide Serenol

Tried Bonafide Serenol

Bonafide Serenol has been gaining attention in women’s health discussions, so one of our team members decided to give it a fair try. She regularly dealt with irritability and mood swings in the days before her cycle and wanted a natural, hormone‑free supplement that could provide some balance.

The directions were clear and required taking two tablets each day with water. The capsules were smooth and easy to swallow. She appreciated that there was no unpleasant aftertaste, which made it easy to stay consistent with the routine.

Within the first week, she noticed a slight improvement in her mood during periods when she typically felt more tense. The change wasn’t dramatic but was noticeable. Results, however, were inconsistent. Some days brought better balance, while others felt unchanged. After 30 days, she described the benefits as modest rather than significant.

Her conclusion was that Bonafide Serenol offered mild relief without side effects and fit well into a daily routine, but it didn’t deliver strong or consistent results. She rated it 6 out of 10 and considered it more suitable for women with lighter PMS concerns.

If you're searching for an alternative to Bonafide Serenol, consider reading the Centrum Menopause Support review. This trusted, research-backed formula is designed to help manage common menopause symptoms, including hot flashes, mood swings, and bone health. It could be the solution you’re looking for.

Watch the Bonafide Serenol Video Review and discover more details.

Side Effects & Safety of Bonafide Serenol

Bonafide Serenol appears to be generally safe for daily use among most adults, especially when taken as directed. The formula includes natural ingredients such as pollen extracts and chromium, both of which are commonly regarded as safe when consumed in moderate amounts.

That said, some individuals may experience mild side effects, particularly those sensitive to bee products. Possible reactions include digestive discomfort, headaches, or mild allergic responses. These effects are usually temporary and tend to resolve on their own without medical treatment.

It is essential to note that Serenol contains royal jelly and pollen, which individuals with allergies to bees, bee products, or pollen should avoid. As with any dietary supplement, women with existing health conditions or those taking prescription medications should consult a healthcare professional before beginning Serenol.

Real Customer Reviews of Bonafide Serenol

Bonafide Serenol is available for purchase on its official website and has been reviewed by customers on platforms like Amazon. However, the product does not currently appear on Trustpilot and is not accredited by the Better Business Bureau (BBB).

At the time of writing, Serenol receives a mix of positive and critical feedback, providing a balanced view of how it works for different individuals.

A top positive review comes from a verified Amazon purchaser, Jennifer Ann, who gave the product 5 out of 5 stars:

“My doctor recommended this to help with hot flashes and night sweats. She said it would take a few months to see any results but I got relief within the first few weeks of use. I am so happy to have found this!! If you are unsure due to the price I totally understand, I was too, but the relief it has given me is worth every penny!”

On the other hand, a critical review from M. Class, another verified purchaser, rated it 1 out of 5 stars:

“Caused severe anxiety, depression and appetite increase… can not return so I am out the money. Only used for a few weeks but more than enough time to see the terrible side effects.”

As with many dietary supplements, individual results can vary. Some users report meaningful relief from PMS and menopause symptoms, while others feel the benefits are minimal or outweighed by side effects. The reviews highlight both the potential and the limitations of Bonafide Serenol depending on personal health factors and sensitivity to ingredients.

Where to Find the Best Value

Bonafide Serenol can be purchased directly from the official Bonafide website. The company offers several purchasing options that can help reduce the monthly cost for those planning to use the supplement long‑term. One bottle contains 60 capsules for a month's supply.

Here’s the pricing breakdown from the official site:

• Single box costs $63 (plus $5 shipping)
• Monthly plan: $48 per month (free shipping)
• 3‑month plan: $43 per month ($129 billed quarterly, free shipping)

Each box contains 180 tablets, which are intended to last three months when taken as directed. The subscription options offer notable savings compared to a one-time purchase, particularly the quarterly plan.

Compared to other hormone‑free PMS support supplements, Bonafide Serenol is positioned in the higher price range. However, the subscription plans offer better value for consistent users and are more cost-effective for long-term use.

Pros and Cons of Bonafide Serenol

Should You Buy Bonafide Serenol?

Customer reviews of Bonafide Serenol are mixed. Some users praise it for helping reduce mood swings, irritability, and hot flashes, and they note improvements in emotional balance within a few weeks. However, others mention little to no improvement, and some report adverse effects such as anxiety or appetite changes. The feedback suggests that while Serenol offers benefits for some, results can be inconsistent and may not always justify the price.

In terms of safety, Bonafide Serenol is generally well‑tolerated when taken as directed. The formula is hormone‑free, which appeals to women who prefer a natural approach to managing menopause symptoms. Still, it contains bee‑derived ingredients like royal jelly and pollen, so individuals with bee or pollen allergies should avoid it. Mild side effects such as digestive upset or headaches have been reported but tend to be temporary.

From an ingredient standpoint, Serenol includes pollen extracts, chromium picolinate, and royal jelly. Pollen extracts and chromium show promise in mood regulation and reducing food cravings. Research on chromium remains limited. Royal jelly, however, is underdosed in this formula compared to clinical studies, so its benefits are questionable. Serenol is often mentioned among the best menopause supplements, but its effectiveness depends on individual needs.

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But what we see with Menocil is different. Menocil takes a different approach when it comes to catering to women undergoing menopause. Instead of pollen extracts, it relies on a blend of botanicals, including red clover, black cohosh, dong quai, wild yam, and ashwagandha (ingredients traditionally used to support hormonal balance and ease menopausal and PMS symptoms). Menocil also includes nutrients like vitamin B6 and other supportive botanicals, providing a broader range of support for both emotional and physical concerns.

While Bonafide Serenol may be appealing for women who want a hormone‑free supplement backed by some research, those seeking more consistent results and broader symptom relief may find Menocil to be the stronger choice. With its comprehensive ingredient profile, better value, and expanded support for emotional and physical symptoms, Menocil stands out as a more reliable option for long‑term use.