Centrum Menopause Support Review: Does It Really Relieve Hot Flashes and Improve Sleep?
Centrum Menopause Support offers a hormone-free solution for hot flashes, sleep issues, and stress relief. But is it truly effective? Read this in-depth review to find out.
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Key Takeaways
- Centrum Menopause Support is a hormone‑free and melatonin‑free supplement created to manage menopause symptoms like hot flashes and poor sleep.
- It is made of three separate supplements: Restful Sleep, Complete Multivitamin + Hot Flash Support, and Clear Mind & Calm Mood.
- Ingredients like Ashwagandha (KSM‑66®) and enXtra® are supported by research to reduce stress, improve alertness, and support menopause comfort.
- While ingredients like DailyZz™ and geniVida® may help, limited evidence and lower doses reduce their effectiveness for hot flash relief.
- Reviews are mixed. Some report fewer hot flashes and better sleep, while others saw little benefit and disliked the tablet size.
- Compared to more comprehensive menopause support products, Centrum Menopause Support may fall short in consistent symptom relief and ingredient dosing.
Introduction
The search for safe, non‑hormonal supplements to manage menopause symptoms like disrupted sleep and hot flashes has expanded significantly in recent years. So, many consumers now seek solutions that do not rely on melatonin or synthetic hormones.
One supplement that’s been attracting attention is Centrum Menopause Support.
Centrum Menopause Support is available in three targeted formulas: Restful Sleep, designed to support nighttime comfort; Complete Multivitamin + Hot Flash Support, which combines vitamins and minerals to help reduce hot flashes; and Clear Mind & Calm Mood, formulated to promote focus and emotional balance.
Centrum Menopause Support claims to be a hormone‑free, melatonin‑free solution intended to help users sleep more soundly and wake up feeling focused and refreshed. The formula aims to provide relief without the morning grogginess sometimes linked to traditional sleep aids.
The question remains whether this supplement delivers the benefits it claims to offer. Do its ingredients align with clinical research, and can it provide meaningful results in daily use?
In this review, we’ll analyze Centrum Menopause Support ingredients, evaluate customer feedback, explore potential side effects, and compare its value with similar menopause support supplements.
This review is designed to provide a balanced and fact-based perspective, allowing you to determine if Centrum Menopause Support is a suitable formula for your needs.
Let’s get started.
Ingredient Analysis – Centrum Menopause Support

We carefully examined the ingredients in Centrum Menopause Support to determine if they truly provide relief for menopause symptoms such as hot flashes, stress, and sleep issues. Here’s what we found:
DailyZz™
DailyZz™ is a botanical blend that combines spearmint extract and green tea extract, standardized for polyphenols such as rosmarinic acid and EGCG. In a 30‑day clinical study, adults who took 485 mg each night reported better sleep quality and fewer insomnia symptoms compared to placebo. They also showed improvements in focus, memory, and concentration the following day, with no major side effects reported.
Despite these benefits, the study did not measure or report outcomes related to hot flashes or vasomotor symptoms. Since DailyZz™ has no established estrogenic effects, it cannot be expected to relieve hot flashes or address hormonal changes associated with menopause. Its evidence base remains specific to sleep and cognition only.
We disapprove of this ingredient.
geniVida® (Genistein)
GeniVida® is a purified form of genistein, an isoflavone often studied for managing menopausal symptoms like hot flashes. A 12‑month RCT tested 56 mg/day of genistein in postmenopausal women. Results showed sustained reductions in hot flashes and improved quality of life, with no significant adverse uterine effects. This indicates that higher doses may be necessary for consistent vasomotor relief.
Centrum Menopause Support provides 30 mg/day, which is almost half the dose used in the most reliable long‑term study. Given that efficacy in reducing hot flashes was demonstrated at nearly double the amount, the current formulation risks being underdosed for meaningful symptom relief.
We disapprove of this ingredient.
Ashwagandha (KSM‑66®)
Ashwagandha is widely used in menopause supplements for its adaptogenic potential to support hormonal balance, reduce stress, and ease vasomotor symptoms such as hot flashes. A randomized, double‑blind, placebo‑controlled trial found that women who took 300 mg of ashwagandha root extract twice daily for 8 weeks experienced meaningful relief from hot flashes. Participants also demonstrated improved Menopause Rating Scale scores and more effective symptom management. Watch this video to learn how ashwagandha can provide effective support during menopause.
The same study reported positive hormonal changes, including decreased follicle-stimulating hormone (FSH) and luteinizing hormone, alongside increased estradiol levels. These changes are significant because they correlate with reduced vasomotor symptoms and improved menopausal quality of life, with minimal side effects. As we discussed in Hormone Harmony Review Article
According to Dr. Sarah Thompson, Expert in Herbal Medicine,
Ashwagandha (KSM-66®) is a highly effective adaptogen for managing menopause symptoms like hot flashes and stress. Research supports its role in improving hormonal balance and overall well-being. Similarly, enXtra® is gaining recognition for enhancing alertness and reducing fatigue, making it a valuable addition for menopause supplements targeting cognitive clarity and emotional balance.
We approve of this ingredient.
enXtra®
EnXtra® is a natural, caffeine‑free ingredient designed to help with alertness and calmness. In a 12‑week randomized trial, adults taking 300 mg per day felt more awake, had quicker reactions, and less fatigue than those taking a placebo. These benefits lasted for about five hours.
The same study confirmed safety, with no cardiovascular issues, sleep disturbances, or adverse events occurring, highlighting the long-term tolerability. Though not tested specifically in menopausal women or for vasomotor symptom relief, enXtra® does appear to support cognitive clarity and stress buffering during menopause.
We approve of this ingredient.
We Tried Centrum Menopause Support

A member of our review team decided to test Centrum Menopause Support firsthand. She had been dealing with restless nights, frequent wake‑ups from hot flashes, and difficulty staying alert during the day. She wanted something straightforward that could support better sleep without relying on melatonin.
The directions for the dietary supplement were easy to follow; it required taking one tablet in the evening before bed. She began with the recommended dosage and monitored how quickly it took effect. The pill was simple to take and didn’t leave any unpleasant aftertaste, which made it more convenient than some powdered supplements she had tried in the past.
Over several weeks, she noticed minor improvements. Her night sweats were slightly less frequent, and she reported sleeping more steadily, though she still woke up occasionally. Morning alertness improved slightly, and she did not experience the drowsiness sometimes associated with sleep aids. She also did not experience side effects such as headaches or stomach upset.
While the supplement offered some benefits, the changes were moderate rather than substantial. She rated it 6.5 out of 10 and noted that it may suit people seeking gentle, hormone-free support, but may not fully meet the expectations of those looking for stronger or faster results.
Side Effects & Safety of Centrum Menopause Support
Centrum Menopause Support is generally considered safe for healthy adults when used as directed. The formulas are hormone-free, melatonin-free, vegetarian-friendly, and made without common allergens such as gluten, dairy, soy, and nuts.
Some individuals may still notice mild side effects. Reports mention occasional digestive discomfort or minor changes in sleep patterns during the initial weeks. These usually lessen as the body becomes accustomed to the supplement.
The product contains clinically studied ingredients, including geniVida and DailyZz, which are not associated with serious health risks at the recommended dosage. Still, those who are pregnant, nursing, under 18, or taking medication for existing conditions should speak with a healthcare provider before beginning use.
Real Customer Reviews of Centrum Menopause Support
Centrum Menopause Support is available at major retailers such as Amazon, CVS, and Walmart. Currently, there is no dedicated Better Business Bureau (BBB) listing or Trustpilot profile specifically for the Centrum Menopause Support line; however, the Centrum brand is listed on Trustpilot with mixed ratings.
On Amazon, the product boasts dozens of verified reviews with an average rating of over 4 stars. This suggests generally positive impressions, although some feedback remains critical.
A top positive review comes from a verified Amazon customer, Baroness, who gave the product 5 out of 5 stars:
Just bought my second bottle and I think it’s working. Hot flashes used to be almost daily, but I haven’t had one since about a week after taking this. I can’t swallow large pills, even this one, so I just toss it into my smoothie machine and drink it daily. Not that it matters, but the pink coating is so pretty!
On the other hand, not all experiences were favorable. A more critical review comes from Carolyn, who rated it 1-star:
I was extremely hopeful this would at least lessen the frequency or severity of hot flashes. It sadly does neither. Just a huge pill to swallow that does nothing.
These reviews reflect a clear divide in user satisfaction. Some customers report experiencing meaningful relief from hot flashes and improved comfort at night, while others say the supplement had little to no effect on their symptoms.
Where to Find the Best Value
Centrum Menopause Support is widely available through major retailers, such as Amazon, Walmart, and CVS. Each formula is designed for daily use and typically comes in a 28‑ to 30‑tablet supply.
Here’s the current pricing breakdown on Amazon:
- Restful Sleep costs $19.93 (28 tablets)
- Complete Multivitamin + Hot Flash Support costs $20.78 (30 tablets)
- Clear Mind & Calm Mood costs $18.81 (30 tablets)
Compared to other menopause support supplements, Centrum Menopause Support is priced in the affordable‑to‑moderate range. The cost per bottle varies slightly between formulas, but all fall under $21, making them more accessible compared to many specialized hormone-free supplements.
Pros and Cons of Centrum Menopause Support
Pros:
- Hormone‑free and melatonin‑free formulas designed for menopause symptom support.
- Widely available through Amazon and other major retailers at an affordable price range.
Cons
- Results may take several weeks to become noticeable, with full benefits for hot flashes typically occurring after 12 weeks.
- Some users report little or no improvement in symptoms.
- Pills may feel large and difficult for some individuals to swallow.
Should You Buy Centrum Menopause Support?
Centrum Menopause Support has received mixed reviews online. Many customers report fewer hot flashes and improved sleep quality, while others note little to no difference. The feedbacks are mixed.
The product is considered safe for most adults. It is hormone‑free, melatonin‑free, and formulated without common allergens. Some users report mild digestive discomfort or early sleep changes, but these typically resolve as the body adjusts.
Two ingredients stand out positively: Ashwagandha (KSM‑66®) and enXtra®. Both have credible research supporting benefits such as reduced stress, improved alertness, and better quality of life for women experiencing menopause.
However, other ingredients may not be as effective in this formula. DailyZz™ appears useful for sleep support but lacks evidence for hot flash relief. geniVida®, while clinically tested, is included in a lower dose than the amount most effective for reducing vasomotor symptoms. This dosing issue makes consistent results less certain.
That’s where Menocil presents a stronger alternative. Menocil combines probiotics, Black Cohosh, Dong Quai, and turmeric with other supportive botanicals to provide broader symptom coverage. Reviews highlight significant relief from hot flashes, improved mood, better sleep, and steadier energy. With a higher satisfaction rating and a 60‑day money‑back guarantee, it offers both reassurance and comprehensive support.
So, if you want a gentle, affordable, hormone‑free product, Centrum Menopause Support may be worth trying. But for more consistent and well‑rounded relief, Menocil appears to deliver a more complete formula that addresses both physical and emotional menopause symptoms effectively. When it comes to the best menopause supplements, finding the right fit for your needs is key.
FAQs
References
Flawless Bloom has strict sourcing policies and relies on primary sources such as medical organizations, academic institutions, governmental agencies, and peer-reviewed scientific journals. Read more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial process.
- Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study - https://pubmed.ncbi.nlm.nih.gov/34553463/
- Physiology, Follicle Stimulating Hormone - https://www.ncbi.nlm.nih.gov/books/NBK535442/
- A Randomized Placebo Controlled Clinical Trial Demonstrating Safety & Efficacy of EnXtra® in Healthy Adults - https://pubmed.ncbi.nlm.nih.gov/32412358/
- A Randomized, Double-Blind, Placebo-Controlled Trial of a Polyphenol Botanical Blend on Sleep and Daytime Functioning - https://pubmed.ncbi.nlm.nih.gov/33809544/
- Estrogen - https://www.ncbi.nlm.nih.gov/books/NBK538260/
- Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT- and placebo-controlled study - https://pubmed.ncbi.nlm.nih.gov/15243277/